Influence of prostate rotation on dose distribution in the target volume
Warsaw Medical Physics Meeting 2015
E. Dąbrowska1,2, B. Brzozowska2, B. Chaber3, P. Kukołowicz1, J. Starzyński3, A. Zawadzka1
1 Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Department of Medical Physics
2 University of Warsaw, Department of Biomedical Physics
3 Faculty of Electrical Engineering, Warsaw University of Technology
The inter-fraction prostate motion can have a significant impact on dose distribution in the target volume. However, the concept of the PTV was developed to minimize the influence of all uncertainties of target position on dose distribution, the problem of rotations is not entirely analyzed. The aim of this study was to investigate the influence of the prostate rotation on delivered dose for three different techniques. Our results showed that the change of dose distribution in the target volume depend on the angle of rotation and the treatment delivery technique. Only rotations larger than about 21o influence significantly on the DVH and the TCP. The 3D-CRT showed the smallest sensitivity to prostate rotations. SIB-IMRT technique was the most sensitive to rotations, however the increased prescribed dose to prostate compensated reduction in the TCP. It remained comparable to the TCP obtained for 3D-CRT and IMRT techniques.
25 minutes 12 seconds